We believe that knowing research methods is not only needed to develop your own study, but serves as the basis for understanding strengths and limitations of medical information and for improving patient care. Learn how its done, learn how it works.
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Readdressing the validity of Repeat Revascularization outcome in PCI vs CABG trials
Pablo Lamelas – In the last decades multiple trials comparing the efficacy of PCI vs CABG incorporated repeat revascularization in the primary composite outcome, which favoured CABG repeatedly, and frequently … Continue reading Readdressing the validity of Repeat Revascularization outcome in PCI vs CABG trials
NOACs in stable CAD with Atrial Fibrillation: with or without aspirin? The AFIRE trial
Fernando Botto – A general rule dictates “the more the antithombotic effect, the higher the risk of bleeding”. In stable CAD patients beyond 1 year of PCI or without prior … Continue reading NOACs in stable CAD with Atrial Fibrillation: with or without aspirin? The AFIRE trial
EXCEL 5-years: Trial-Based Vs Evidence-Based Medicine
Pablo Lamelas – In TCT 2019 Dr Stone published the results of EXCEL trial at 5-years which triggered many controversies in TCT, EACTS, social media, etc. Does this 5-year report … Continue reading EXCEL 5-years: Trial-Based Vs Evidence-Based Medicine
New TAVR studies: Weak design not the solution for small trials
Pablo Lamelas – In TCT 2019 two trials testing different TAVR designs were presented: SCOPE I (ACURATE neo vs Sapien 3) and Portico IDE trial (Portico vs other devices available). … Continue reading New TAVR studies: Weak design not the solution for small trials
THEMIS trial: when significant is not significant
Fernando Botto – ESC 2019 hot line sessions delivered us enough evidence to discuss methods and patient-centered decisions. For instance, dual antiplatelet treatment came up with a new trial in … Continue reading THEMIS trial: when significant is not significant
