Rethinking the Interpretation of Randomized Trials: A Reflection on CLOSURE-AF

A few days ago, the CLOSURE AF Trial was published online at NEJM. It was accompanied by an editorial titled “another overused method in Cardiology”. Friends sent me links to … Continue reading Rethinking the Interpretation of Randomized Trials: A Reflection on CLOSURE-AF

Oral anticoagulation in Atrial Fibrillation with CHA2DS2-VASc = 1: too much uncertainty?

Fernando Botto – Patients with any form of Atrial Fibrillation (AF) having an estimated thromboembolic risk (stroke or systemic embolism) of 1% or more per year should be considered for … Continue reading Oral anticoagulation in Atrial Fibrillation with CHA2DS2-VASc = 1: too much uncertainty?